Cheng Hong, MD, PhD

Subspecialty Interest

Hematology/Hematopathology
Head and neck pathology

Board Certification

Anatomic Pathology and Clinical Pathology
Hematology/Hematopathology

Fellowship

Hematopathology at Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, NY

Residency

Chief resident & Resident, AP/CP, Rutgers University (UMDNJ) –New Jersey Medical School, Newark, NJ

Medical School

Qingdao University Medical College, Qingdao, China

Publication/Presentations

  • Cheng H Diagnostic challenges in lymphoma with aberrant markers. Oral presentation at The 5th annual CAPA Diagnostic course 2019, Los Angeles, CA
  • Cheng H T-cell Prolymphocytic Leukemia and Associated Symptoms. Oral presentation at Atlantic Regional Hematopathology Meeting 2019, Philadelphia, PA
  • Cheng H PAX5 Negative Classic Hodgkin Lymphoma. Oral presentation at Atlantic Regional Hematopathology Meeting 2018, Philadelphia, PA
  • Cheng H CD3 negative/CD20positive T-cell lymphoma. Poster presentation at Atlantic Regional Hematopathology Meeting, 2017, Philadelphia, PA
  • Cheng H High grade B-cell lymphoma lack of pan B-cell markers. Oral presentation at Atlantic Regional Hematopathology Meeting 2016, Philadelphia, PA

  • Cheng H EBV Postive B-cell lymphoma arising from angioimmunoblastic T-cell lymphoma. Oral presentation at Atlantic Regional Hematopathology Meeting 2015, Philadelphia, PA
  • Cheng H, Feldman T, Butt Y, Chow KF, Yang XY, Bhattacharyya PK, DeVinck DC. T-cell Prolymphocytic Leukemia with Extensive Cardiovascular Infiltrate Leading to Multiple Myocardial Infarcts and Cardiac Death. Texas Heart Institute Journal 2014, Dec 1;41(6):626-30.
  • Cheng H Pediatric Follicular Lymphoma vs. Reactive Lymphadenopathy. Oral presentation at Atlantic Regional Hematopathology Meeting 2014, Philadelphia, PA
  • Cheng H. New Multiantibody Strategy of Eight Color Flow Cytometry for Paucicellular Specimens. Poster presentation at Research Day of Albert Einstein College of Medicine, 2014, Bronx, NY
  • Cheng H, Feldman T, Chow KF, Mato A, Panush D, Yang XY, Goy A, Mazzella FM, Bhattacharyya PK. PEG-Asparaginase Based Multidrug Chemotherapy is Effective for Refractory Disseminated Extranodal NK/T-Cell Lymphoma With Leptomentigeal Involvement: A Clinical Case Report and Review of Literature. J Hematology 2013; 2(1):31-36
  • Rampur, L.; Kaushik, D.; Cheng, H.; Jariwala, S. Recurrent Angioedema as a Manifestation of Mast Cell Activation Syndrome Poster presentation at American College of Allergy, Asthma & Immunology Annual meeting, 2013, Baltimore, MA
  • Cheng H. T-cell Prolymphocytic Leukemia with Extensive Cardiovascular Infiltrate Leading to Multiple Myocardial Infarcts and Cardiac Death. Poster presentation at T-cell lymphoma forum, 2013, San Francisco, CA.
  • Cheng H. Extranodal NK/T-cell Lymphoma, Nasal Type, Presenting with Primary Cutaneous Lesion Mimicking Blastic Plasmacytoid Dendritic Cell Neoplasm. Poster presentation at T-cell lymphoma forum, 2012, San Francisco, CA.
  • Cheng H, Khan N, Roger JE, Swaroop A. Excess cones in the retinal degeneration rd7 mouse, caused by the loss of function of orphan nuclear receptor Nr2e3, originate from early-born photoreceptor precursors. Hum Mol Genet. 2011 20 (21): 4102-15.
  • Cheng H. Chemotherapy of dexamethasone, methotrexate, and pegasparaginase for refractory extranodal NK/T-cell lymphoma with brain involvement. Poster presentation at T-cell lymphoma forum, 2011, San Francisco, CA.
  • Yu J, Yu J, Mani RS, Cao Q, Brenner CJ, Cao X, Wang X, Wu L, Li J, Hu M, Gong Y, Cheng H, Laxman B, Vellaichamy A, Shankar S, Li Y, Dhanasekaran SM, Morey R, Barrette T, Lonigro RJ, Tomlins SA, Varambally S, Qin ZS, Chinnaiyan AM. An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression. Cancer cell. 2010 May 18; 17(5):443-54.
  • Cheng H. Novel transcript fusion SLC45C3-ELK4 variants in prostate cancer. Poster presented at 99th United States and Canadian Academy of Pathology Annual Meeting; 2010, Washington D. C.
  • Oh EC, Cheng H, Hao H, Jia L, Khan N, Swaroop A. Rod differentiation factor NRL activates the expression of nuclear receptor NR2E3 to suppress the development of cone photoreceptor. Brain Res. 2008 Oct 21; 1236:16-29.
  • Cheng H Stem Cells in Age-related Eye Diseases. Oral Presentation presented at: ARVO annual meeting 2007; Fort Lauderdale, FL
  • Cheng H Treat Retinal Diseases with Subretinal Transplantation of Photoreceptor Precursors. Oral Presentation presented at: 23rd Annual Research Day, 2007; Ann Arbor, MI.
  • Cheng H. Subretinal Transplantation of Photoreceptor Precursors: A Promising Therapy for Retinal Disease. Poster presented at: 23rd Annual Research Day; 2007, Ann Arbor, MI.
  • Cheng H. Subretinal transplantation of purified cone precursors in mouse cone degeneration mutants. Poster presented at: ARVO annual meeting; 2007, Fort Lauderdale, FL.
  • Cheng H, Aleman TS, Cideciyan AV, Khanna R, Jacobson SG, Swaroop A. In vivo function of the orphan nuclear receptor NR2E3 in establishing photoreceptor identity during mammalian retinal development. Hum Mol Genet. 2006 Sep; 15(17): 2588-602.
  • Chang B, Khanna H, Hawes N, Jimeno D, He S, Lillo C, Parapuram SK, Cheng H, Scott A, Hurd RE, Sayer JA, Otto EA, Attanasio M, O’Toole JF, Jin G, Shou C, Hildebrandt F, Williams DS, Heckenlively JR, Swaroop A. In-frame deletion in a novel centrosomal/ciliary protein CEP290/NPHP6 perturbs its interaction with RPGR and results in early-onset retinal degeneration in the rd16 mouse. Hum Mol Genet. 2006 Jun; 15(11): 1847-57.
  • Akimoto M, Cheng H, Zhu D, Brzezinski JA, Khanna R, Filippova E, Oh EC, Jing Y, Linares JL, Brooks M, Zareparsi S, Mears AJ, Hero A, Glaser T, Swaroop A. Targeting of GFP to newborn rods by Nrl promoter and temporal expression profiling of flow-sorted photoreceptors. Proc Natl Acad Sci U S A. 2006 Mar; 103(10): 3890-5.
  • Cheng H The orphan nuclear receptor NR2E3 establishes rod photoreceptor identity during retinal neurogenesis. Oral Presentation presented at: 22nd Annual Research Day, 2006; Ann Arbor, MI.
  • Cheng H. The orphan nuclear receptor NR2E3 directs photoreceptor precursors to rod pathway. Poster presented at: 9th Annual Great Lakes Vision Research Conference; 2006, Ann Arbor, MI.
  • Cheng H. Dual Function of The Orphan Nuclear Receptor Nr2e3 In Rod Photoreceptor Differentiation. Poster presented at: 65th Society for Developmental Biology Annual Meeting; 2006, Ann Arbor, MI.
  • Cheng H. The orphan nuclear receptor NR2E3 plays dual function in rod photoreceptor differentiation. Poster presented at: Gordon Research Conferences-Visual System Development; 2006, Il Ciocco, Lucca (Barga), Italy.
  • Zhu D, Hero AO, Cheng H, Khanna R, Swaroop A. Network constrained clustering for gene microarray data. 2005 Nov; 21(21): 4014-20.
  • Cheng H. Network constrained clustering for gene microarray data. Poster presented at: ISMB annual meeting; 2005, Detroit, MI.
  • Cheng H. The photoreceptor specific nuclear receptor NR2E3 (PNR) regulates rod differentiation. Poster presented at: 6th International symposium on Stem Cells and Organogenesis; 2005, Ann Arbor, MI.
  • Cheng H. The Photoreceptor Specific Nuclear Receptor NR2E3 (PNR) Is a Direct Target of NRL and Can Induce Rod Differentiation. Poster presented at: ARVO annual meeting; 2005, Ann Arbor, MI.
  • Friedman JS, Khanna H, Swain PK, Denicola R, Cheng H, Mitton KP, Weber CH, Hicks D, Swaroop A. The minimal transactivation domain of the basic motif-leucine zipper transcription factor NRL interacts with TATA-binding protein. J Biol Chem. 2004 Nov; 279(45): 47233-41.
  • Bumsted O’Brien KM, Cheng H, Jiang Y, Schulte D, Swaroop A. The photoreceptor-specific nuclear receptor NR2E3 is specifically expressed in rod photoreceptors of human retina. Invest Ophthalmol Vis Sci. 2004 Aug; 45(8): 2807-12.
  • Cheng H, Khanna H, Oh EC, Hicks D, Mitton KP, Swaroop A. Photoreceptor specific orphan nuclear receptor Nr2e3 functions as a transcriptional activator in rod photoreceptors. Hum Mol Genet. 2004 Aug; 13(15): 1563-75.
  • Cheng H. NR2E3, a photoreceptor specific nuclear receptor, acts as an activator in photoreceptor differentiation. Poster presented at: Laboratory mouse in vision research (Jackson Laboratory); 2004, Bar Harbor, ME.
  • Cheng H. Regulation of photoreceptor gene expression and differentiation by NR2E3, a photoreceptor specific nuclear receptor. Poster presented at: 24th annual CMB symposium and poster session; 2004, Ann Arbor, MI.
  • Cheng H. Photoreceptor specific nuclear receptor NR2E3 functions as a transcriptional activator in rod photoreceptors. Poster presented at: Gordon Research Conferences-Visual system development; 2004, Bristol, RI.
  • Cheng H. Interaction of NR2E3, a Photoreceptor-specific Nuclear Receptor, and REV-ERBa: Possible role in photoreceptor gene regulation and differentiation. Poster presented at: ARVO annual meeting; 2004, Fort Lauderdale, FL.
  • Cheng H. The minimal transactivation domain of the basic motif-leucine zipper protein NRL interacts with TATA-binding protein. Poster presented at: ARVO annual meeting; 2004, Fort Lauderdale, FL.
  • Cheng H. Interaction of NR2E3, a photoreceptor specific nuclear receptor, and REV-ERB alpha: possible role in photoreceptor differentiation and function. Poster presented at: Society for Neuroscience Annual Meeting; 2003, New Orleans, LA.
  • Cheng H. Role of NR2E3, a photoreceptor-specific nuclear receptor, in the retina development and photoreceptor differentiation. Poster presented at: 23rd annual CMB symposium and poster session; 2003, Ann Arbor, MI.
  • Benndorf R, Sun X, Gilmont RR, Biederman KJ, Molloy MP, Goodmurphy CW, Cheng H, Andrews PC, Welsh MJ. HSP22, a new member of the small heat shock protein superfamily, interacts with mimic of phosphorylated HSP27 ((3D)HSP27). J Biol Chem.. 2001 Jul; 276(29): 26753-61.

Awards and Honors

Cheng Hong, MD, PhD

Cheng Hong, MD, PhD

  • Postdoctoral Intramural Research Training Award
    National Institute of Health, Bethesda, MD – 2008
  • Center for Organogenesis Postdoctoral Fellowship
    University of Michigan, Ann Arbor, MI – 2007 and 2006
  • Kellogg Eye Center Postdoctoral Fellowship
    University of Michigan, Ann Arbor, MI – 2006
  • Nominee for Distinguished Dissertation Awards
    University of Michigan, Ann Arbor, MI – 2006
  • Center for Organogenesis Travel Award, U of Michigan – 2006
  • Rackham Travel Grant, U of Michigan – 2006 and 2005
  • Gordon Research Conference Travel Grant Award – 2006 and 2004
  • Horace H. Rackham Predoctoral Fellowship
    University of Michigan, Ann Arbor, MI – 2005
  • Outstanding Student Publication Award
    University of Michigan, Ann Arbor, MI – 2004
  • Jackson Laboratory Travel Award – 2004
  • Retina Research Foundation/Joseph M. and Eula C.
    Lawrence Travel Grant Award
    Association for Research in Vision and Ophthalmology – 2004

Affiliate Medical Centers & Resources